| Bioactivity | Duazomycin A is a glutamine antagonist. Duazomycin A can significantly enhance the effectiveness of 6-Mercaptopurine (6-MP) (HY-13677) in experimental allergic encephalomyelitis (EAE) without increasing toxicity[1][2]. |
| CAS | 2508-89-6 |
| Formula | C8H11N3O4 |
| Molar Mass | 213.19 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Vogel C L, et al. Enhanced suppression of experimental allergic encephalomyelitis by combination chemotherapy with duazomycin-A and 6-mercaptopurine[J]. Proceedings of the Society for Experimental Biology and Medicine, 1969, 131(1): 251-256. [2]. Rosenberg S, et al. Enhanced Suppression of the Secondary Immune Response by Combination of 6-Mercaptopurine ‘Duazomycin A’[J]. Nature, 1963, 199(4898): 1101-1102. |