| Bioactivity | DuP 747 hydrochloride is an analgesic with selective kappa-opioid receptor agonist activity. DuP 747 showed less spiradoline-appropriate selection when administered SC, but showed a partial generalized response to spiradoline when administered IP or PO. The 5-hydroxy-desmethoxy metabolite of DuP 747 induced selection of the saline-appropriate lever only. The effects of DuP 747 suggest that its metabolites may play a major role in the similar responses to spiradoline after IP and PO administration[1]. |
| CAS | 115904-74-0 |
| Formula | C24H29Cl3N2O2 |
| Molar Mass | 483.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Assessing spiradoline-like discriminative effects of DuP 747: influence of route of administration |
DuP 747 hydrochloride
CAS: 115904-74-0 F: C24H29Cl3N2O2 W: 483.86
DuP 747 hydrochloride is an analgesic with selective kappa-opioid receptor agonist activity. DuP 747 showed less spirado
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