| Bioactivity | DuP 714 is an oral active thrombin inhibitor with the IC50 values of 150 nM aganist thrombin-induced aggregation in washed human platelets. DuP 714 can be used for study of arterial thrombosi[1][2]. |
| CAS | 130982-43-3 |
| Formula | C21H33BN6O5 |
| Molar Mass | 460.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Reilly TM, et al. Effect of thrombin inhibitors on platelet functions: comparative analysis of DuP 714 and hirudin. Blood Coagul Fibrinolysis. 1992;3(5):513-517. [2]. Mitchell TJ, et al. Analysis of the thrombin inhibitor DuP 714 by an enzyme-linked immunosorbent assay. Blood Coagul Fibrinolysis. 1994;5(4):517-521. |