| Bioactivity | Drupacine is a natural product, that can be isolated from Cephalotaxus harringtonia. Drupacine shows nematotoxicity and anticancer activity[1][2]. |
| Invitro | Drupacine 对 HCT-116 有细胞毒性作用，IC50 为 16.20 ± 3.44 μM[1]。Drupacine 对松材线虫的 ED50 为 27.1 μg/mL，对南方根结线虫 (Meloidogyne incognita) 的 ED50 为 76.3 μg/mL[2]。 |
| Name | Drupacine |
| CAS | 49686-57-9 |
| Formula | C18H21NO5 |
| Molar Mass | 331.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li Y, et al. Preparation of Stereo-Divergent Compounds from the Natural Product Drupacine Based on Complexity-to-Diversity Strategy. Chem Biodivers. 2023 Jun;20(6):e202300263. [2]. Wen Y, et al. Nematotoxicity of drupacine and a Cephalotaxus alkaloid preparation against the plant-parasitic nematodes Meloidogyne incognita and Bursaphelenchus xylophilus. Pest Manag Sci. 2013 Sep;69(9):1026-33. |