Bioactivity | Droloxifene, a Tamoxifen derivative, is an orally active and selective estrogen receptor modulator. Droloxifene shows antiestrogenic and anti-implantation effects. Droloxifene induces p53 expression and apoptosis in MCF-7 cells. Droloxifene prevents bone loss in ovariectomized rats [1][2][3]. | ||||||||||||
Invitro | Droloxifene (10 nM; 16-18 hours) induces apoptosis in MCF-7 cells[1]. Cell Viability Assay[2] Cell Line: | ||||||||||||
Name | Droloxifene | ||||||||||||
CAS | 82413-20-5 | ||||||||||||
Formula | C26H29NO2 | ||||||||||||
Molar Mass | 387.51 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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