| Bioactivity | Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor[1]. Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity[1][2][3][4][5]. |
| Invitro | Doxycycline hydrochloride (0.01-10 µg/mL, 4 d) affects growth of glioma cells only under high concentrations[2].Doxycycline hydrochloride (0.01-10 µg/mL, 24 h) decreases MT-CO1 protein content with concentrations of 1 µg/mL and higher in SVG cells[2].Doxycycline hydrochloride (100 ng/mL, 1 µg/mL; 24 h) reduces proliferation of human cell lines[4].Doxycycline hydrochloride (0-250 μM, 72 h) inhibits cell viability of breast cancer cells [5]. Cell Viability Assay[2] Cell Line: |
| Name | Doxycycline hydrochloride |
| CAS | 10592-13-9 |
| Formula | C22H25ClN2O8 |
| Molar Mass | 480.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Doxycycline hydrochloride
CAS: 10592-13-9 F: C22H25ClN2O8 W: 480.90
Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxy
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