| Bioactivity | Doxepin-d3 (hydrochloride) is a deuterium labeled Doxepin Hydrochloride. Doxepin hydrochloride is an orally active tricyclic antidepressant. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2[1][2]. | ||||||||||||
| Target | Histamine receptor H1; CYP450 2C19 and CYP450 1A2 | ||||||||||||
| Name | Doxepin-d3 (hydrochloride) | ||||||||||||
| CAS | 347840-07-7 | ||||||||||||
| Formula | C19H19D3ClNO | ||||||||||||
| Molar Mass | 318.86 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Hajak, G., et al., Doxepin in the treatment of primary insomnia: a placebo-controlled, double-blind, polysomnographic study. J Clin Psychiatry, 2001. 62(6): p. 453-63. [2]. Gillman PK1. Tricyclic antidepressant pharmacology and therapeutic drug interactions updated. Br J Pharmacol. 2007 Jul;151(6):737-48. |
Doxepin-d3 (hydrochloride)
CAS: 347840-07-7 F: C19H19D3ClNO W: 318.86
Doxepin-d3 (hydrochloride) is a deuterium labeled Doxepin Hydrochloride. Doxepin hydrochloride is an orally active tricy
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