| Bioactivity | Dopaminechrome (DACHR), an oxidation product of dopamine (HY-B0451), can facilitate the generation of H2O2 at brain mitochondrial complex I in a concentration- and respiration-dependent manner. Dopaminechrome possesses neurotoxicity and can be utilized in research on Parkinson's disease[1][2]. |
| CAS | 39984-17-3 |
| Formula | C8H7NO2 |
| Molar Mass | 149.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zoccarato F, et al. Dopamine-derived dopaminochrome promotes H(2)O(2) release at mitochondrial complex I: stimulation by rotenone, control by Ca(2+), and relevance to Parkinson disease. J Biol Chem. 2005 Apr 22;280(16):15587-94. [2]. Sivakumar P, et al. Review on the interactions between dopamine metabolites and α-Synuclein in causing Parkinson's disease[J]. Neurochemistry International, 2023, 162: 105461. |
Dopaminechrome
CAS: 39984-17-3 F: C8H7NO2 W: 149.15
Dopaminechrome (DACHR), an oxidation product of dopamine (HY-B0451), can facilitate the generation of H2O2 at brain mito
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