| Bioactivity | Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity[1]. | ||||||||||||
| Target | D2R | ||||||||||||
| Name | Dopamine D2 receptor antagonist-1 | ||||||||||||
| CAS | 1055411-77-2 | ||||||||||||
| Formula | C14H17N3S | ||||||||||||
| Molar Mass | 259.37 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Fyfe TJ, et al. Subtle modifications to a thieno[2,3-d]pyrimidine scaffold yield negative allosteric modulators and agonists of the dopamine D2 receptor. Eur J Med Chem. 2019 Apr 15;168:474-490. |
Dopamine D2 receptor antagonist-1
CAS: 1055411-77-2 F: C14H17N3S W: 259.37
Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM
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