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Dodecyltrimethylammonium-d25 (bromide)

CAS: 2309360-05-0 F: C15H9D25BrN W: 333.50

Dodecyltrimethylammonium-d25 (bromide) is the deuterium labeled Dodecyltrimethylammonium (bromide). Dodecyltrimethylammo
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Dodecyltrimethylammonium-d25 (bromide) is the deuterium labeled Dodecyltrimethylammonium (bromide)[1]. Dodecyltrimethylammonium bromide (DTAB) is a surfactant. Dodecyltrimethylammonium bromide interacts with DNA and changes the mechanical properties of DNA on binding and the specific binding parameters of the interaction[2].
Invitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name Dodecyltrimethylammonium-d25 (bromide)
CAS 2309360-05-0
Formula C15H9D25BrN
Molar Mass 333.50
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. E F Silva, et al. Dodecyltrimethylammonium bromide surfactant effects on DNA: Unraveling the competition between electrostatic and hydrophobic interactions.