| Bioactivity | Afatinib (dimaleate) (Standard) is the analytical standard of Afatinib (dimaleate). This product is intended for research and analytical applications. Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer. |
| CAS | 693-23-2 |
| Formula | C12H22O4 |
| Molar Mass | 230.30 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Dodecanedioic acid (Standard)
CAS: 693-23-2 F: C12H22O4 W: 230.30
Afatinib (dimaleate) (Standard) is the analytical standard of Afatinib (dimaleate). This product is intended for researc
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This product is for research use only, not for human use. We do not sell to patients.