| Bioactivity | Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm[1]. |
| Target | MMP3 |
| Name | Dnp-PYAYWMR |
| CAS | 135662-06-5 |
| Sequence | {DNP}-Pro-Tyr-Ala-Tyr-Trp-Met-Arg |
| Shortening | {DNP}-PYAYWMR |
| Formula | C54H65N13O14S |
| Molar Mass | 1152.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li Y, et al. Combination of serum matrix metalloproteinase-3 activity and EBV antibodies improves the diagnostic performance of nasopharyngeal carcinoma. J Cancer. 2020 Aug 18;11(20):6009-6018. |
Dnp-PYAYWMR
CAS: 135662-06-5 F: C54H65N13O14S W: 1152.24
Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (non
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