Bioactivity | Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (Disitamab vedotin (HY-P9985))[1]. |
In Vivo | Disitamab (27 mg/kg; i.v.; once; 5 mL/kg) shows no significant toxicity in monkeys[1]. |
Name | Disitamab |
CAS | 2185868-98-6 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jiang J, et al. Preclinical safety profile of disitamab vedotin:a novel anti-HER2 antibody conjugated with MMAE. Toxicol Lett. 2020;324:30-37. |