| Bioactivity | Dipyridamole is an orally active phosphodiesterase (PDE) inhibitor. Dipyridamole also is an antiplatelet agent used in secondary prophylaxis against stroke. Dipyridamole can induce cancer cell-specific apoptosis[1][2][3]. |
| Invitro | Dipyridamole (5 μM; 15 min) results in a 2.5-fold increase in intracellular cAMP levels in OCI-AML-3 cells[2].Dipyridamole (5 μM; 48 h) with the statin combination induces apoptosis in primary AML cells[2].Dipyridamole (5 μM; 48 h) possesse cAMP/PKA-independent activity against statininduced SREBP2 activation[2]. Apoptosis Analysis[2] Cell Line: |
| Name | Dipyridamole |
| CAS | 58-32-2 |
| Formula | C24H40N8O4 |
| Molar Mass | 504.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |