| Bioactivity | Diosbulbin D is a potential hepatotoxic compound that can be isolated from Dioscorea bulbifera L.. Diosbulbin D induces apoptosis in L-02 cells[1]. |
| Invitro | Diosbulbin D (10-80 μM; 12-72 h) 可诱导人正常肝脏 L-02 细胞毒性[1]。Diosbulbin D (40 μM; 24 h) 诱导 L-02 细胞形态改变[1]。Diosbulbin D (20-80 μM; 12-48 h) 诱导 L-02 细胞凋亡，并呈时间和浓度依赖性[1]。Diosbulbin D (20-80 μM; 24 h) 诱导 L-02 细胞 caspase 3 的激活[1]。 Cell Viability Assay[1] Cell Line: |
| Name | Diosbulbin D |
| CAS | 66756-57-8 |
| Formula | C19H20O6 |
| Molar Mass | 344.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ma M, et al. The furano norclerodane diterpenoid disobulbin-D induces apoptosis in normal human liver L-02 cells. Exp Toxicol Pathol. 2012 Sep;64(6):611-8. |