| Bioactivity | Dioctanoylglycol (Ethylene glycol dicaprylate), a diacylglycerol analog, is a diacylglycerol kinase (DGK) inhibitor (Ki of 58 μM)[1]. |
| Invitro | Dioctanoylglycol (Dioctanoylethylene glycol) inhibits diacylglycerol phosphorylation in platelets (70-100% at 100 μM) leading to a longer-lived diacylglycerol signal[1]. |
| Name | Dioctanoylglycol |
| CAS | 627-86-1 |
| Formula | C18H34O4 |
| Molar Mass | 314.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. W R Bishop, et al. Attenuation of sn-1,2-diacylglycerol second messengers by diacylglycerol kinase. Inhibition by diacylglycerol analogs in vitro and in human platelets. J Biol Chem. 1986 May 25;261(15):6993-7000. |
Dioctanoylglycol
CAS: 627-86-1 F: C18H34O4 W: 314.46
Dioctanoylglycol (Ethylene glycol dicaprylate), a diacylglycerol analog, is a diacylglycerol kinase (DGK) inhibitor (Ki
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