Bioactivity | Dinophysistoxin 1 (DTX 1, 35-methylokadaic acid) is a causative agent of diarrhetic shellfish poisoning. Dinophysistoxin 1 exerts tumor-promoting activity, serves as a skin irritant as well[1]. |
Invitro | Dinophysistoxin 1 抑制特定的 [3H] 冈田酸与小鼠表皮颗粒部分的结合[1]。 |
In Vivo | Dinophysistoxin 1 (5 μg/mouse; 涂抹在背部; 每周 2 次, 共 30 周) 导致 100 μg 7,12-二甲基苯蒽 (DMBA) 处理组的荷瘤小鼠比例增加[1]。 |
Name | Dinophysistoxin 1 |
CAS | 81720-10-7 |
Formula | C45H70O13 |
Molar Mass | 819.03 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Fujiki H, et al. Diarrhetic shellfish toxin, dinophysistoxin-1, is a potent tumor promoter on mouse skin. Jpn J Cancer Res. 1988 Oct;79(10):1089-93. |