| Bioactivity | Dinaline (GOE 1734; PD 104 208; NSC 328786) is a potent and orally activity anticancer agent. Dinaline shows cytotoxicity and antitumor activity. Dinaline has the potential for the research of colorectal cancer[1]. |
| Invitro | Dinaline (0.47-15 µg/mL; 48, 27 h) 对 SW707、SW948 细胞表现出细胞毒性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Dinaline 相关抗体: Cell Cytotoxicity Assay[1] Cell Line: |
| In Vivo | Dinaline (5.9, 7.7, 10 mg/kg; p.o.; 5 days per week for 10 weeks) 可抑制大鼠的肿瘤生长[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 58338-59-3 |
| Formula | C13H13N3O |
| Molar Mass | 227.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Seelig MH, et al. Efficacy of dinaline and its methyl and acetyl derivatives against colorectal cancer in vivo and in vitro. Eur J Cancer. 1996 Oct;32A(11):1968-76. |