| Bioactivity | Diminazene is an aromatic diamidine compound primarily utilized for the control of trypanosomiasis, a disease caused by trypanosome parasites. Diminazene primarily binds to the kinetoplast DNA (kDNA) of the trypanosomes, interfering with their replication process. Diminazene also presents avenues for novel pharmacological applications, such as acting as an activator of angiotensin-converting enzyme 2 (ACE2), and showing potential in the treatment of hypertension, rheumatoid arthritis, and as an immunomodulator[1]. |
| CAS | 536-71-0 |
| Formula | C14H15N7 |
| Molar Mass | 281.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. da Silva Oliveira G L, et al. Diminazene aceturate—an antiparasitic drug of antiquity: advances in pharmacology & therapeutics[J]. Pharmacological research, 2015, 102: 138-157. |