Dimethomorph_product_DataBase

Bioactivity	Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM[1][2][3].
Invitro	Dimethomorph 抑制卵菌 Phytophthora capsici，P. citrophthora，和 P. parasitica，其 EC50 分别为 <0.1 µg/mL、0.14 µg/mL 和 0.38 µg/mL[1]。Dimethomorph 在 MDA-kb2 人乳腺癌细胞的报告测定中抑制 AR 活性，但在酵母抗雄激素筛选中没有抑制作用 (IC50s = 0.263 和 38.5 µM)[2]。
Name	Dimethomorph
CAS	110488-70-5
Formula	C21H22ClNO4
Molar Mass	387.86
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. M E Matheron, et al. Impact of Azoxystrobin, Dimethomorph, Fluazinam, Fosetyl-Al, and Metalaxyl on Growth, Sporulation, and Zoospore Cyst Germination of Three Phytophthora spp. Plant Dis. 2000 Apr;84(4):454-458. [2]. Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119(6):794-800. [3]. Yigal Cohen,, et al. Differential Activity of Carboxylic Acid Amide Fungicides Against Various Developmental Stages of Phytophthora infestans. Phytopathology. 2007 Oct;97(10):1274-83.

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