| Bioactivity | Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions[1][2][3]. |
| Invitro | Dimethindene maleate (1-1000 μM) suppresses the cromakalim-induced/glibenclamide-sensitive K+ currents in a concentration-dependent and reversible manner with an IC50 value of 29.5 μM[2].Dimethindene maleate (1-1000 μM) inhibits Y-26763-induced glibenclamide-sensitive K+ currents with an IC50 value of 49 μM[2]. |
| Name | Dimethindene maleate |
| CAS | 3614-69-5 |
| Formula | C24H28N2O4 |
| Molar Mass | 408.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |