| Bioactivity | Diflucortolone valerate is a powerful corticosteroid used topically for the research of various skin diseases[1]. | ||||||||||||
| Invitro | Diflucortolone valerate is a potent corticosteroid esterified with valeric acid. Diflucortolone valerate helps reduce swelling, itching, and redness[1]. | ||||||||||||
| In Vivo | DL50 values are virtually non-toxic after single oral administration (mouse greater than 4 g/kg, rat ca. 3.1 g/kg, dog greater than 1 g/kg). Given s.c. (LD50 mouse ca. 180 mg/kg, rat ca. 13 mg/kg) and i.p. (LD50 mouse ca. 450 mg/kg, rat ca. 98 mg/kg) it is highly active and therefore produces also toxic effects[2]. | ||||||||||||
| Name | Diflucortolone valerate | ||||||||||||
| CAS | 59198-70-8 | ||||||||||||
| Formula | C27H36F2O5 | ||||||||||||
| Molar Mass | 478.57 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. B M Henz, et al. Double-blind, Multicentre Analysis of the Efficacy of Borage Oil in Patients With Atopic Eczema. Br J Dermatol. 1999 Apr;140(4):685-8. [2]. V P Günzel, et al. [Toxicological Examination of Pure Diflucortolone Valerate and Its Formulations as Ointment, Fatty Ointment and Cream in Animal Experiments (Author's Transl)]. Arzneimittelforschung. 1976;26(7b):1476-9. |
Diflucortolone valerate
CAS: 59198-70-8 F: C27H36F2O5 W: 478.57
Diflucortolone valerate is a powerful corticosteroid used topically for the research of various skin diseases.
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This product is for research use only, not for human use. We do not sell to patients.