Diflubenzuron-d4_product_DataBase

Bioactivity	Diflubenzuron-d4 is the deuterium labeled Diflubenzuron[1]. Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities[2][3].
Invitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name	Diflubenzuron-d4
CAS	1219795-45-5
Formula	C14H5D4ClF2N2O2
Molar Mass	314.71
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Ker RF. Investigation of locust cuticle using the insecticide diflubenzuron. J Insect Physiol. 1977;23(1):39-48. [3]. Arnold C. Grosscurt, et al. Diflubenzuron: Some aspects of its ovicidal and larvicidal mode of action and an evaluation of its practical possibilities. Pest Management Science.

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