| Bioactivity | Diflorasone act as a corticosteroid hormone receptor agonist with anti-inflammatory and immunosuppressive properties. Diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorticoid receptor (GR) in the cytoplasm. Diflorasone is used for the research of skin diseases such as eczema or psoriasis[1]. | ||||||||||||
| Target | IC50: corticosteroid hormone receptor | ||||||||||||
| Name | Diflorasone | ||||||||||||
| CAS | 2557-49-5 | ||||||||||||
| Formula | C22H28F2O5 | ||||||||||||
| Molar Mass | 410.45 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Wickrema Sinha AJ, et al. Percutaneous absorption and excretion of tritium-labeled diflorasone diacetate, a new topical corticosteroid in the rat, monkey and man. J Invest Dermatol. 1978 Dec;71(6):372-7. |
Diflorasone
CAS: 2557-49-5 F: C22H28F2O5 W: 410.45
Diflorasone act as a corticosteroid hormone receptor agonist with anti-inflammatory and immunosuppressive properties. Di
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