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Diethyl pyrocarbonate

CAS: 1609-47-8 F: C6H10O5 W: 162.14

Diethyl pyrocarbonate is a potent, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vi
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Bioactivity Diethyl pyrocarbonate is a potent, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues[1].
Name Diethyl pyrocarbonate
CAS 1609-47-8
Formula C6H10O5
Molar Mass 162.14
Appearance Liquid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. E E Nattie. Diethyl pyrocarbonate (an imidazole binding substance) inhibits rostral VLM CO2 sensitivity. J Appl Physiol (1985). 1986 Sep;61(3):843-50.