| Bioactivity | Diclofenac amide is a prodrug for Diclofenac sodium (HY-15037). Diclofenac amide is an orally active inhibitor for COX-1/2, that inhibits the production of prostaglandins (PG) and thromboxanes (TX). Diclofenac amide exhibits anti-inflammatory efficacy in Carrageenan (HY-125474)-induced rat paw edema model without causing gastric ulcer (300 μmol/kg)[1]. | ||||||||||||
| CAS | 15362-40-0 | ||||||||||||
| Formula | C14H9Cl2NO | ||||||||||||
| Molar Mass | 278.14 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Santos JL, et al., Pharmacological evaluation and preliminary pharmacokinetics studies of a new diclofenac prodrug without gastric ulceration effect. Int J Mol Sci. 2012 Nov 19;13(11):15305-20. |
Diclofenac amide
CAS: 15362-40-0 F: C14H9Cl2NO W: 278.14
Diclofenac amide is a prodrug for Diclofenac sodium (HY-15037). Diclofenac amide is an orally active inhibitor for COX-1
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