Bioactivity | Deulorlatinib (compound A), a deuterated derivative of Lorlatinib (HY-12215), is a potent inhibitor of tyrosine kinase demonstrating desirable safety and durable activity in ALK-positive advanced NSCLC[1][2]. |
CAS | 2131126-33-3 |
Formula | C21H16D3FN6O2 |
Molar Mass | 409.43 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Shenzhen TargetRx, Inc. Process for preparation of macrocycle. World Intellectual Property Organization, WO2017148325 A1 2017-09-08 |