| Bioactivity | Desoxypeganine (Deoxypeganine) hydrochloride, an alkaloid, is a potent and orally active cholinesterase (BChE and AChE) and selective MAO-A inhibitor, with IC50 values of 2, 17, and 2 μM, respectively. Desoxypeganine hydrochloride can be used for alcohol abuse research[1]. |
| In Vivo | Desoxypeganine hydrochloride (10-30 mg/kg，灌胃，每天一次，连续 16 天) 剂量依赖性地降低乙醇摄入量和乙醇偏好[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 61939-05-7 |
| Formula | C11H13ClN2 |
| Molar Mass | 208.69 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Doetkotte R, et al. Reduction of voluntary ethanol consumption in alcohol-preferring Alko alcohol (AA) rats by desoxypeganine and galanthamine. Eur J Pharmacol. 2005 Oct 17;522(1-3):72-7. [2]. Zheng XY, et al. Acetylcholinesterase inhibitive activity-guided isolation of two new alkaloids from seeds of Peganum nigellastrum Bunge by an in vitro TLC- bioautographic assay. Arch Pharm Res. 2009 Sep;32(9):1245-51. |
Desoxypeganine hydrochloride
CAS: 61939-05-7 F: C11H13ClN2 W: 208.69
Desoxypeganine (Deoxypeganine) hydrochloride, an alkaloid, is a potent and orally active cholinesterase (BChE and AChE)
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