Bioactivity | Desethoxy Quetiapine dihydrochloride (Compound 28) is an antagonist for dopamine D2 receptor with an IC50 of 1330 nM. Desethoxy Quetiapine dihydrochloride antagonises Apomorphine (HY-12723)-induced climbing and swimming disruption in mouse models[1]. |
CAS | 329218-14-6 |
Formula | C19H23Cl2N3OS |
Molar Mass | 412.38 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Warawa EJ, et al., Behavioral approach to nondyskinetic dopamine antagonists: identification of seroquel. J Med Chem. 2001 Feb 1;44(3):372-89. |