| Bioactivity | Dermaseptin-B3 inhibits the growth of Gram-positive and Gram-negative bacteria (MIC: 1.3, 2.3, 5.0, 2.6, 2.3 μM for S. aureus, P. aeruginosa, P. aeruginosa, E. (ATCC 25922), E. (54127) respectively). Dermaseptin-B3 also inhibits tumor cell proliferation[1][2]. |
| Name | Dermaseptin-B3 |
| CAS | 210890-55-4 |
| Sequence | Ala-Leu-Trp-Lys-Asn-Met-Leu-Lys-Gly-Ile-Gly-Lys-Leu-Ala-Gly-Gln-Ala-Ala-Leu-Gly-Ala-Val-Lys-Thr-Leu-Val-Gly-Ala |
| Shortening | ALWKNMLKGIGKLAGQAALGAVKTLVGA |
| Formula | C127H219N35O32S |
| Molar Mass | 2780.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Charpentier S, et al. Structure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics. J Biol Chem. 1998 Jun 12;273(24):14690-7. [2]. van Zoggel H, et al . Antitumor and angiostatic peptides from frog skin secretions. Amino Acids. 2012 Jan;42(1):385-95. |
Dermaseptin-B3
CAS: 210890-55-4 F: C127H219N35O32S W: 2780.38
Dermaseptin-B3 inhibits the growth of Gram-positive and Gram-negative bacteria (MIC: 1.3, 2.3, 5.0, 2.6, 2.3 μM for S.
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This product is for research use only, not for human use. We do not sell to patients.