| Bioactivity | Deoxyharringtonine is an alkaloid isolated from Cephalotaxus genus with significant anti-leukemic activity[1]. |
| Invitro | Deoxyharringtonine 作用于 P388 白血病细胞的 IC50 值为 7.5 ng/mL。此外，其对造血细胞系如 HL-60、HL-60/RV+、JURKAT、ALL3、NCEB1、JEKO、MOLT-3 等具有极强的细胞毒活性[1]。 |
| Name | Deoxyharringtonine |
| CAS | 36804-95-2 |
| Formula | C28H37NO8 |
| Molar Mass | 515.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Joseph D Eckelbarger, et al. Synthesis of antiproliferative Cephalotaxus esters and their evaluation against several human hematopoietic and solid tumor cell lines: uncovering differential susceptibilities to multidrug resistance. Chemistry. 2008;14(14):4293-306. |