| Bioactivity | Demethylcantharidate disodium, an endogenous metabolite, induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer[1]. |
| Invitro | Demethylcantharidate (0-100 μM; 0, 12, 24, 48 or 72 hours) disodium inhibits HCC cell proliferation[1].Demethylcantharidate (0, 9, 18 or 36 µM; 24 hours) disodium dose dependently increases the levels of cleaved caspase-3, cleaved caspase-9, and Bax/Bcl-2[1]. Cell Viability Assay[1] Cell Line: |
| Name | Demethylcantharidate disodium |
| CAS | 129-67-9 |
| Formula | C8H8Na2O5 |
| Molar Mass | 230.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Demethylcantharidate disodium
CAS: 129-67-9 F: C8H8Na2O5 W: 230.13
Demethylcantharidate disodium, an endogenous metabolite, induces apoptosis in hepatocellular carcinoma cells via ER stre
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