| Bioactivity | Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids[1]. | ||||||||||||
| Invitro | Delamanid inhibits the synthesisi of mucolic acids, cruciala component of the cell wall of the Mycobacterium tuberculosis complex[1].Delamanid shows more potent antibacterial activity against drug-susceptible and drug-resistant strains of M. tuberculosis[2]. Delamanid do not affect rifampin, pyrazinamide, and isoniazid exposure; the ethambutol AUCτ and Cmax values are about 25% higher with delamanid coadministration[3]. | ||||||||||||
| Name | Delamanid | ||||||||||||
| CAS | 681492-22-8 | ||||||||||||
| Formula | C25H25F3N4O6 | ||||||||||||
| Molar Mass | 534.48 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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