PeptideDB

DefNEtTrp

CAS: F: C30H27N9O3S W: 593.66

DefNEtTrp is a Fe dual chelator ligand, consisting of the Def and Trp moieties. DefNEtTrp exhibits potent and broad-spec
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Bioactivity DefNEtTrp is a Fe dual chelator ligand, consisting of the Def and Trp moieties. DefNEtTrp exhibits potent and broad-spectrum antiproliferative and cell death behavior in cancer cell lines. DefNEtTrp induces both apoptosis and ferroptosis and has cytotoxicity with an IC50 value of 0.77 μM[1].
Formula C30H27N9O3S
Molar Mass 593.66
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Rodríguez I, et al. DefNEtTrp: An Iron Dual Chelator Approach for Anticancer Application. JACS Au. 2024 Dec 4;4(12):4799-4808.