| Bioactivity | Decatransin, a fungal cyclic decadepsipeptide, is a protein translocation inhibitor. Decatransin inhibits co- and post-translational translocation across the Sec61/SecYEG translocon[1]. |
| Invitro | Decatransin 抑制蛋白质易位到共翻译和翻译后易位底物的内质网[1]。Decatransin (compound 1) 显示出对哺乳动物细胞系（例如 HCT116 人结肠癌细胞和 COS-1 猴肾细胞）的有效生长抑制作用，IC50 为 30-140 nM。Decatransin 还抑制酵母 S. cerevisiae 的生长，IC50 约为 2 µM[1]。 |
| Name | Decatransin |
| Formula | C63H109N9O12 |
| Molar Mass | 1184.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |