| Bioactivity | Daphnetin (Standard) is the analytical standard of Daphnetin. This product is intended for research and analytical applications. Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively. Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1 , ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research. |
| CAS | 486-35-1 |
| Formula | C9H6O4 |
| Molar Mass | 178.14 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Daphnetin (Standard)
CAS: 486-35-1 F: C9H6O4 W: 178.14
Daphnetin (Standard) is the analytical standard of Daphnetin. This product is intended for research and analytical appli
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This product is for research use only, not for human use. We do not sell to patients.