| Bioactivity | Daphnegiravone D (compound 70) is an HDAC6 inhibitor with anti-hepatocellular carcinoma activity. Daphnegiravone D can induce apoptosis and selectively inhibit the proliferation of liver cancer cells through the p38 and JNK MAPK pathways[1]. |
| CAS | 2581826-37-9 |
| Formula | C26H28O6 |
| Molar Mass | 436.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang D, et al. A new Prenylated Flavonoid induces G0/G1 arrest and apoptosis through p38/JNK MAPK pathways in Human Hepatocellular Carcinoma cells. Sci Rep. 2017 Jul 18;7(1):5736. [2]. Chen JJ, et al. Network pharmacology predicted HDAC6 as a potential target of flavones from Daphne giraldii on hepatocellular carcinoma. Nat Prod Res. 2021 Sep;35(18):3171-3175. |
Daphnegiravone D
CAS: 2581826-37-9 F: C26H28O6 W: 436.50
Daphnegiravone D (compound 70) is an HDAC6 inhibitor with anti-hepatocellular carcinoma activity. Daphnegiravone D can i
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