Bioactivity | Dansyl-D-Ala-Gly-Phe(pNO2)-Gly is a synthetic peptide substrate. As a substrate of NEP, Dansyl-D-Ala-Gly-Phe(pNO2)-Gly can be specifically recognized and cleaved by the enzyme, thereby releasing the fluorophore dansyl, which can be quantitatively detected. Therefore, it is often used to determine the activity of NEP[1]. |
CAS | 83960-27-4 |
Sequence | {Dansyl}-{d-Ala}-Gly-{Phe(pNO2)}-Gly |
Shortening | {Dansyl}-{d-Ala}-G-{Phe(pNO2)}-G |
Formula | C28H32N6O9S |
Molar Mass | 628.65 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Niikura T, et al. A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice[J]. PloS one, 2011, 6(1): e16259. |