Bioactivity | Daeatal (Dynorphin A ethylamide (1-9)) is an ethylamine-modified dynorphin fragment that can be used in the study of analgesia, addiction, depression, etc. Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease[1]. |
CAS | 103614-28-4 |
Sequence | Me-Tyr-Gly-Gly-Phe-Leu-Arg-{Arg(Me)}-{d-Leu}-Arg-{NH-Et} |
Shortening | Me-YGGFLR-{Arg(Me)}-{d-Leu}-R-{NH-Et} |
Formula | C56H93N19O10 |
Molar Mass | 1192.46 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75. |