| Bioactivity | DYR684 is a PROTAC of the protein kinases DYRK1A. DYR684 promotes fast, efficient, potent, and selective degradation of DYRK1A in cell-based assays. (Pink: ligand for target protein (HY-168195); Black: linker (HY-168200); Blue: ligand for E3 ligase (HY-168198))[1]. |
| CAS | 3038487-48-5 |
| Formula | C58H58FN15O5 |
| Molar Mass | 1064.18 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wilms G, et, al. Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B. J Med Chem. 2024 Oct 10;67(19):17259-17289. |
DYR684
CAS: 3038487-48-5 F: C58H58FN15O5 W: 1064.18
DYR684 is a PROTAC of the protein kinases DYRK1A. DYR684 promotes fast, efficient, potent, and selective degradation of
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