| Bioactivity | DXR-IN-3 is a DXR inhibitor that specifically targets Toxoplasma gondii. DXR-IN-3 shows in vitro activity against the TgDXR enzyme, with an IC50 value of 0.62 μM and a Ki value of 0.19 μM. DXR-IN-3 can inhibit the proliferation of Toxoplasma, with an IC50 value of 5.46 μM[1]. |
| CAS | 1465907-72-5 |
| Formula | C10H12Cl2NO5PS |
| Molar Mass | 360.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mazzone F, et al. 1-Deoxy-d-xylulose 5-phosphate reductoisomerase as target for anti Toxoplasma gondii agents: crystal structure, biochemical characterization and biological evaluation of inhibitors. Biochem J. 2024 Aug 21;481(16):1075-1096. |
DXR-IN-3
CAS: 1465907-72-5 F: C10H12Cl2NO5PS W: 360.15
DXR-IN-3 is a DXR inhibitor that specifically targets Toxoplasma gondii. DXR-IN-3 shows in vitro activity against the Tg
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