Bioactivity | DT-3 acetate is a membrane-permeable protein kinase G Iα (PKG Iα) inhibitory peptide and shows pharmacological blockade of the cGMP-PKG signalling[1]. | ||||||
Sequence | Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Leu-Arg-Lys-Lys-Lys-Lys-Lys-His | ||||||
Shortening | RQIKIWFQNRRMKWKKLRKKKKKH | ||||||
Formula | C152H258N52O28S.xC2H4O2 | ||||||
Molar Mass | 3294.07 (free acid) | ||||||
Appearance | 固体 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
||||||
Reference | [1]. Shinichi Takahashi, et al. Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. J Physiol. 2008 Sep 1;586(17):4209-23. |