| Bioactivity | DSPE-PEG-Biotin (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Target | PEGs |
| Invitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| Name | DSPE-PEG-Biotin (MW 5000) |
| CAS | 385437-57-0 |
| Molar Mass | 5000(Average) |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |