| Bioactivity | DRAK2-IN-1, compound 16, is a potent, selective and ATP-competitive DRAK2 inhibitor with IC50and Kivalues of 3 nM and 0.26 nM, respectively.DRAK2-IN-1 also has inbitory effect on DRAK1 (IC50=51 nM)[1]. | ||||||||||||
| Target | IC50: 3 nM (DRAK2); 51 nM (DRAK1); 1.8 μM (DRPK2); 2.3 μM (DRAK2); 1.8 μM (DRPK3) | ||||||||||||
| Name | DRAK2-IN-1 | ||||||||||||
| CAS | 871837-60-4 | ||||||||||||
| Formula | C21H20N4O3 | ||||||||||||
| Molar Mass | 376.41 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Jung ME, et al.Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening.Bioorg Med Chem Lett. 2016 Jun 1;26(11):2719-23 |
DRAK2-IN-1
CAS: 871837-60-4 F: C21H20N4O3 W: 376.41
DRAK2-IN-1, compound 16, is a potent, selective and ATP-competitive DRAK2 inhibitor with IC50and Kivalues of 3 nM and 0.
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