DQ661

CAS: 2027551-01-3 F: C41H47Cl2N5O2 W: 712.75

DQ661 is a potent PPT1 inhibitor. DQ661 is a dimeric quinacrine autophagy inhibitor. DQ661 inhibits mTORC1 activity. DQ6

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Bioactivity	DQ661 is a potent PPT1 inhibitor. DQ661 is a dimeric quinacrine autophagy inhibitor. DQ661 inhibits mTORC1 activity. DQ661 decreases the protein expression of pS6K T389, pS6 S240-244. DQ661 shows anticancer activity[1][2].
CAS	2027551-01-3
Formula	C41H47Cl2N5O2
Molar Mass	712.75
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Nicastri MC, et al. Dimeric quinacrines as chemical tools to identify PPT1, a new regulator of autophagy in cancer cells. Mol Cell Oncol. 2017 Nov 30;5(1):e1395504. [2]. Rebecca VW, et al. A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles. Cancer Discov. 2017 Nov;7(11):1266-1283.