Bioactivity | DPQ hydrochloride (6, 7-dimethoxy-2 -(1-piperazinyl)-4-quinazolinamine hydrochloride) is a PARP1 inhibitor, with IC50 value of 40 nM. DPQ hydrochloride has anti-inflammatory and antiviral activity. DPQ hydrochloride is used to study acute lung injury[1][2]. |
Name | DPQ hydrochloride |
CAS | 84050-22-6 |
Formula | C14H20ClN5O2 |
Molar Mass | 325.79 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wang G, et al. PARP-1 inhibitor, DPQ, attenuates LPS-induced acute lung injury through inhibiting NF-κB-mediated inflammatory response. PLoS One. 2013 Nov 21;8(11):e79757. [2]. Bottini A, et al. Targeting Influenza A Virus RNA Promoter. Chem Biol Drug Des. 2015 Oct;86(4):663-73. |