PeptideDB

DPQ hydrochloride

CAS: 84050-22-6 F: C14H20ClN5O2 W: 325.79

DPQ hydrochloride (6, 7-dimethoxy-2 -(1-piperazinyl)-4-quinazolinamine hydrochloride) is a PARP1 inhibitor, with IC50 va
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Bioactivity DPQ hydrochloride (6, 7-dimethoxy-2 -(1-piperazinyl)-4-quinazolinamine hydrochloride) is a PARP1 inhibitor, with IC50 value of 40 nM. DPQ hydrochloride has anti-inflammatory and antiviral activity. DPQ hydrochloride is used to study acute lung injury[1][2].
Name DPQ hydrochloride
CAS 84050-22-6
Formula C14H20ClN5O2
Molar Mass 325.79
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Wang G, et al. PARP-1 inhibitor, DPQ, attenuates LPS-induced acute lung injury through inhibiting NF-κB-mediated inflammatory response. PLoS One. 2013 Nov 21;8(11):e79757. [2]. Bottini A, et al. Targeting Influenza A Virus RNA Promoter. Chem Biol Drug Des. 2015 Oct;86(4):663-73.