Bioactivity | DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively).[9][1]. |
Invitro | DPP-8/9 probe-1 (compound 20) (10 μM; 30 min) 可显著染色并可视化 THP 细胞中的 DPP-8/9[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> DPP-8/9 probe-1 相关抗体: Immunofluorescence[1] Cell Line: |
CAS | 3020859-80-4 |
Formula | C31H36FN7O7 |
Molar Mass | 637.66 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Espadinha M, et al. Active site-directed probes targeting dipeptidyl peptidases 8 and 9. Eur J Med Chem. 2024 Apr 15;270:116389. |