Bioactivity | DPC 961 (DMP 961) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). DPC 961 is a potent and specific inhibitor of HIV-1 reverse transcriptase, which inhibits the activity of HIV-1 reverse transcriptase in a non-competitive manner, thereby preventing viral replication. DPC 961 can be used for research on AIDS[1]. |
CAS | 214287-88-4 |
Formula | C14H10ClF3N2O |
Molar Mass | 314.69 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mutlib A, et al. Characterization of Novel Glutathione Adducts of a Non-Nucleoside Reverse Transcriptase Inhibitor,(S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-3, 4-dihydro-2 (1 H)-quinazolinone (DPC 961), in Rats. Possible Formation of an Oxirene Metabolic Intermediate from a Disubstituted Alkyne[J]. Chemical research in toxicology, 2000, 13(8): 775-784. |