| Bioactivity | DNA gyrase B-IN-2 (Compound E) is a 2-aminobenzothiazole-based DNA gyrase B inhibitor with promising activity against ESKAPE bacterial pathogens. DNA gyrase B-IN-2 showed low nanomolar inhibition of DNA gyrase (IC50 E. coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae.DNA gyrase B-IN-2 can be used for the research of infection[1]. |
| Target | IC50: DNA gyrase (< 10 nM). |
| Name | DNA gyrase B-IN-2 |
| Formula | C18H18Cl2N4O4S |
| Molar Mass | 457.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sterle M, et al. Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens. ACS Omega. 2023 Jun 28;8(27):24387-24395. |
DNA gyrase B-IN-2
CAS: F: C18H18Cl2N4O4S W: 457.33
DNA gyrase B-IN-2 (Compound E) is a 2-aminobenzothiazole-based DNA gyrase B inhibitor with promising activity against ES
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This product is for research use only, not for human use. We do not sell to patients.