| Bioactivity | DNA-PK-IN-12 (compound 31t) is an oral active DNA-PK inhibitor with the IC50 of 0.1 nM. DNA-PK-IN-12 inhibits cell growth and Hct116 cell colony formation with the IC50 of 33.28 μM, and shows antitumor activity in vivo[1]. |
| Name | DNA-PK-IN-12 |
| CAS | 2792146-91-7 |
| Formula | C21H24N8O2 |
| Molar Mass | 420.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liu K, et al. Discovery, Optimization, and Evaluation of Potent and Selective DNA-PK Inhibitors in Combination with Chemotherapy or Radiotherapy for the Treatment of Malignancies. J Med Chem. Published online December 20, 2023. |
DNA-PK-IN-12
CAS: 2792146-91-7 F: C21H24N8O2 W: 420.47
DNA-PK-IN-12 (compound 31t) is an oral active DNA-PK inhibitor with the IC50 of 0.1 nM. DNA-PK-IN-12 inhibits cell growt
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.